Topic
Inflammation and oxidative stress
Blood markers that move with inflammation or with oxidative stress.
This page is not a ranking. Ingredients appear in order of how much we have read here.

The 11 things measured here · ingredients read against each
- High-sensitivity CRP 11
- Malondialdehyde 6
- Homocysteine 5
- Oxidative stress (F2-isoprostanes) 4
- Interleukin-6 3
- Total Antioxidant Capacity 3
- Tumor Necrosis Factor alpha (TNF-α) 3
- Superoxide Dismutase Activity 2
- Glutathione Peroxidase Activity 1
- Interleukin-8 (IL-8) 1
- Matrix Metalloproteinase-3 (Stromelysin-1) 1
Read here so far: 40 questions across 22 ingredients
Curcumin
- Curcumin and High-sensitivity CRPTwo sources, all measured lowerModerate certainty, level 3 of 4
- Curcumin and Interleukin-6Two sources, all measured lowerModerate certainty, level 3 of 4
- Curcumin and MalondialdehydeTwo sources, all measured lowerModerate certainty, level 3 of 4
- Curcumin and Total Antioxidant CapacityTwo sources, all measured higherModerate certainty, level 3 of 4
- Curcumin and Tumor Necrosis Factor alpha (TNF-α)Two sources, all measured lowerModerate certainty, level 3 of 4
- Curcumin and Superoxide Dismutase ActivityOne source, measured higherModerate certainty, level 3 of 4
N-acetylcysteine
- N-acetylcysteine and HomocysteineTwo sources, all measured lowerModerate certainty, level 3 of 4
- N-acetylcysteine and MalondialdehydeTwo sources, all measured lowerModerate certainty, level 3 of 4
- N-acetylcysteine and High-sensitivity CRPTwo sources, saying different thingsLow certainty, level 2 of 4
- N-acetylcysteine and Total Antioxidant CapacityTwo sources, all found no clear differenceLow certainty, level 2 of 4
Coenzyme Q10
- Coenzyme Q10 and High-sensitivity CRPTwo sources, all measured lowerVery low certainty, level 1 of 4
- Coenzyme Q10 and Interleukin-6One source, measured lowerLow certainty, level 2 of 4
- Coenzyme Q10 and Oxidative stress (F2-isoprostanes)One source, measured lowerLow certainty, level 2 of 4
Selenium
- Selenium and Glutathione Peroxidase ActivityOne source, measured higher, and one source carries a noticeLow certainty, level 2 of 4
- Selenium and MalondialdehydeOne source, measured lower, and one source carries a noticeLow certainty, level 2 of 4
- Selenium and Total Antioxidant CapacityOne source, measured higher, and one source carries a noticeLow certainty, level 2 of 4
Astaxanthin
- Astaxanthin and MalondialdehydeOne source, found no clear differenceLow certainty, level 2 of 4
- Astaxanthin and High-sensitivity CRPOne source, reported mixed resultsVery low certainty, level 1 of 4
Boron
- Boron and High-sensitivity CRPOne source, measured lowerVery low certainty, level 1 of 4
- Boron and Tumor Necrosis Factor alpha (TNF-α)One source, measured lowerVery low certainty, level 1 of 4
Copper
- Copper and Superoxide Dismutase ActivityOne source, found no clear differenceLow certainty, level 2 of 4
- Copper and Oxidative stress (F2-isoprostanes)One source, measured lowerVery low certainty, level 1 of 4
Ginger
- Ginger and Interleukin-6Two sources, saying different thingsModerate certainty, level 3 of 4
- Ginger and High-sensitivity CRPOne source, measured lowerVery low certainty, level 1 of 4
Quercetin
- Quercetin and High-sensitivity CRPOne source, measured lowerLow certainty, level 2 of 4
- Quercetin and Tumor Necrosis Factor alpha (TNF-α)One source, found no clear differenceLow certainty, level 2 of 4
Taurine
- Taurine and High-sensitivity CRPOne source, measured lowerLow certainty, level 2 of 4
- Taurine and MalondialdehydeOne source, measured lowerLow certainty, level 2 of 4
Berberine
- Berberine and High-sensitivity CRPTwo sources, all measured lowerVery low certainty, level 1 of 4
Boswellia serrata
- Boswellia serrata and Matrix Metalloproteinase-3 (Stromelysin-1)One source, measured lowerLow certainty, level 2 of 4
Choline
- Choline and HomocysteineOne source, measured lowerLow certainty, level 2 of 4
Folate
- Folate and HomocysteineOne source, measured lowerModerate certainty, level 3 of 4
Glycine
- Glycine and Oxidative stress (F2-isoprostanes)One source, measured lowerVery low certainty, level 1 of 4
L-Carnitine
- L-Carnitine and High-sensitivity CRPOne source, measured lowerVery low certainty, level 1 of 4
Lactobacillus rhamnosus GG
- Lactobacillus rhamnosus GG and Interleukin-8 (IL-8)Two sources, saying different thingsVery low certainty, level 1 of 4
Melatonin
- Melatonin and Oxidative stress (F2-isoprostanes)One source, measured lowerVery low certainty, level 1 of 4
Piperine
- Piperine and High-sensitivity CRPThree sources, saying different thingsLow certainty, level 2 of 4
Vitamin B12
- Vitamin B12 and HomocysteineOne source, measured lowerModerate certainty, level 3 of 4
Vitamin B6
- Vitamin B6 and HomocysteineOne source, found no clear differenceLow certainty, level 2 of 4
Vitamin E
- Vitamin E and MalondialdehydeOne source, measured lowerVery low certainty, level 1 of 4
Where the sources say different things
Every side in full, because one line would have to pick one of them.
Each bar is one source’s range, drawn against the line of no difference: left of the line is lower, right is higher. Widths are not comparable between rows.
Piperine and high-sensitivity CRP
Three sources here, and they say different things: two measured lower high-sensitivity CRP and one found no clear difference.
One source’s range. The sources here say different things. Randomised trial, 2015 · 117 participants
Ginger and interleukin-6
Two sources here, and they say different things: one measured lower interleukin-6 and one found no clear difference.
One source’s range, crossing no difference: these numbers fit no effect too. The sources here say different things. Systematic review, 2020
N-acetylcysteine and high-sensitivity CRP
Two sources here, and they say different things: one measured lower high-sensitivity CRP and one found no clear difference.
One source’s range, crossing no difference: these numbers fit no effect too. The sources here say different things. Systematic review, 2020
Lactobacillus rhamnosus GG and interleukin-8 (IL-8)
Two sources here, and they say different things: one measured lower interleukin-8 (IL-8) and one reported mixed results.
-66 percent change
Mechanism study, 2008
How much of this is one source
Read from 38 sources. 26 of the 40 questions here rest on a single source with nothing yet to check them against, and on 4 questions the sources say different things.
What is still to read is kept per ingredient, not per topic, so every ingredient named above carries its own list.
Still to read means nobody here has got to it, not that it was tried and did nothing or that no research exists. A pairing on no list is not a gap: we never set out to read it.
The other 14 topics
- Sleep29 questions · 11 ingredients
- Mood, stress and thinking34 questions · 18 ingredients
- Heart and blood pressure50 questions · 24 ingredients
- Cholesterol and blood fats70 questions · 24 ingredients
- Blood sugar and insulin52 questions · 21 ingredients
- Energy and exercise27 questions · 18 ingredients
- Joints, muscles and pain18 questions · 16 ingredients
- Bone strength10 questions · 6 ingredients
- Hormones, thyroid and fertility30 questions · 12 ingredients
- Liver, kidney and digestion22 questions · 14 ingredients
- Skin, hair and nails7 questions · 4 ingredients
- Vitamin and mineral levels15 questions · 9 ingredients
- Body weight and composition16 questions · 11 ingredients
- Long-term health and immunity20 questions · 17 ingredients
This is a library, not advice. No recommendation, no dose, no diagnosis, no ranking. We never ask about your symptoms, and nothing here is tailored to you.